结合ox40的抗体及其用途

Antibodies that bind to OX40 and their uses

Abstract

本发明涉及结合人OX40的拮抗剂抗体或其片段。更具体而言,本发明涉及结合人OX40的拮抗剂抗体或其片段,其包括包含SEQ ID NO:1的氨基酸序列的重链CDR1,和/或包含SEQ ID NO:2的氨基酸序列的重链CDR2,和/或包含SEQ ID NO:3的氨基酸序列的重链CDR3;和/或包括包含SEQ ID NO:4的氨基酸序列的轻链CDR1,和/或包含SEQ ID NO:5的氨基酸序列的轻链CDR2,和/或包含SEQ ID NO:6的氨基酸序列的轻链CDR3。
The present invention relates to antagonist antibodies or fragments thereof that bind to human OX40. More specifically, the present invention relates to an antagonist antibody or fragment thereof that binds to human OX40 comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO:1, and/or a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO:2, and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO:3; and/or comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO:4, and/or a light chain CDR2 comprising the amino acid sequence of SEQ ID NO:5 and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO:6.

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Cited By (1)

    Publication numberPublication dateAssigneeTitle
    WO-2017063162-A1April 20, 2017苏州丁孚靶点生物技术有限公司Anti-ox40 antibody and application thereof